Prof. Sergio P. Acebrón

Microenvironmental Cell Biology

Since 2026, Scientific Director of EHU-iBio

Ikerbasque Research Professor at University of Basque Country (EHU)

Professor and Head of the Dept of. Cell signalling & Genome stability at Heidelberg University

Hella Bühler Preis 2021 for “outstanding work in cancer research”, Cancer Research UK Career development award 2017 (Declined), DAAD European Witness appointment in 2017.

Co-founder and former president (2012 – 2014) of the Society of Spanish Researchers in Germany (CERFA). Director of Science+ (2015 – 2019).

Previous research experience at Heidelberg University (Germany, 2017 – present), and German Cancer Research Center – DKFZ (Germany, 2009 – 2017)

Doctor in Biochemistry and Molecular Biology (2008) from University of the Basque Country (Spain)

Selected Publications

Smarduch, S., et al. “A Novel Biosensor for the Spatiotemporal Analysis of Sting Activation During Innate Immune Responses to dsDNA.” EMBO J 44.7 (2025)
de Jaime-Soguero, A., et al. “Developmental Signals Control Chromosome Segregation Fidelity During Pluripotency and Neurogenesis by Modulating Replicative Stress.” Nature Communications 15.1 (2024)
van den Berg, J., et al. “Quantifying DNA Replication Speeds in Single Cells by Scedu-Seq.” Nature Methods 21.7 (2024)
Bufe, A., et al. “Wnt Signaling Recruits Kif2a to the Spindle to Ensure Chromosome Congression and Alignment During Mitosis.” PNAS118.34 (2021)
Giebel, N., et al. “Usp42 Protects Znrf3/Rnf43 from R-Spondin-Dependent Clearance and Inhibits Wnt Signalling.” EMBO Reports 22.5 (2021)
Koch, S., et al., “Post-transcriptional Wnt signaling governs epididymal sperm maturation.” CELL 5 1225-1236 (2016)
Acebrón , SP., et al., ” Mitotic wnt signaling promotes protein stabilization and regulates cell size.” Molecular Cell 54, 4 (2014)
Cruciat, CM., et al., “Requirement of prorenin receptor and vacuolar H+-ATPase–mediated acidification for Wnt signalingSCIENCE 327 (2009)

Publication list (Google scholar)